Intergenerational School Projects: Examples and Guidelines

The residential, educational, and recreational patterns of modern American society tend to isolate the young from the old. Because there is little interaction between the age groups, each generation tends to stereotype the other. Educators must realize that these age-related stereotypes affect our interpersonal relationships, our self-images, and, consequently, our potential to live a full, rewarding life

Float-polishing process and analysis of float-polished quartz

A fluid-mechanical model is developed for the float-polishing process. In this model laminar flow between the sample and the lap results in pressure gradients at the grooves that support the sample on a fluid layer. The laminar fluid motion also produces supersmooth, damage-free surfaces. Quartz substrates for applications in high-stress environments were float polished, and their surfaces were analyzed by optical scatterometry, photoacoustic spectroscopy, and atomic force microscopy. The removal of 100 µm of material by a lapping-polishing process, with final float polishing, left low levels of subsurface damage, with a surface roughness of approximately 0.2-nm rms

Delayed Decision-making in Real-time Beatbox Percussion Classification

This is an electronic version of an article published in Journal of New Music Research, 39(3), 203-213, 2010. doi:10.1080/09298215.2010.512979. Journal of New Music Research is available online at: www.tandfonline.com/openurl?genre=article&issn=1744-5027&volume=39&issue=3&spage=20

Lonely adatoms in space

There is a close relation between the problems of second layer nucleation in epitaxial crystal growth and chemical surface reactions, such as hydrogen recombination, on interstellar dust grains. In both cases standard rate equation analysis has been found to fail because the process takes place in a confined geometry. Using scaling arguments developed in the context of second layer nucleation, I present a simple derivation of the hydrogen recombination rate for small and large grains. I clarify the reasons for the failure of rate equations for small grains, and point out a logarithmic correction to the reaction rate when the reaction is limited by the desorption of hydrogen atoms (the second order reaction regime)

1862-03-30 Major Stowell informs Governor Washburn of the status of the regiment and of Colonel Hight\u27s disappointment

https://digitalmaine.com/cw_me_1st_cav/1234/thumbnail.jp

1862-06-05 D.P. Stowell writes Governor Washburn about the injustices done to him

https://digitalmaine.com/cw_me_1st_cav/1286/thumbnail.jp

1862-04-14 D.P. Stowell writes regarding the regiment

https://digitalmaine.com/cw_me_1st_cav/1249/thumbnail.jp

Audio Event Detection using Weakly Labeled Data

Acoustic event detection is essential for content analysis and description of multimedia recordings. The majority of current literature on the topic learns the detectors through fully-supervised techniques employing strongly labeled data. However, the labels available for majority of multimedia data are generally weak and do not provide sufficient detail for such methods to be employed. In this paper we propose a framework for learning acoustic event detectors using only weakly labeled data. We first show that audio event detection using weak labels can be formulated as an Multiple Instance Learning problem. We then suggest two frameworks for solving multiple-instance learning, one based on support vector machines, and the other on neural networks. The proposed methods can help in removing the time consuming and expensive process of manually annotating data to facilitate fully supervised learning. Moreover, it can not only detect events in a recording but can also provide temporal locations of events in the recording. This helps in obtaining a complete description of the recording and is notable since temporal information was never known in the first place in weakly labeled data.Comment: ACM Multimedia 201

Regulation of protein O-glycosylation by the endoplasmic reticulum–localized molecular chaperone Cosmc

Regulatory pathways for protein glycosylation are poorly understood, but expression of branchpoint enzymes is critical. A key branchpoint enzyme is the T-synthase, which directs synthesis of the common core 1 O-glycan structure (T-antigen), the precursor structure for most mucin-type O-glycans in a wide variety of glycoproteins. Formation of active T-synthase, which resides in the Golgi apparatus, requires a unique molecular chaperone, Cosmc, encoded on Xq24. Cosmc is the only molecular chaperone known to be lost through somatic acquired mutations in cells. We show that Cosmc is an endoplasmic reticulum (ER)–localized adenosine triphosphate binding chaperone that binds directly to human T-synthase. Cosmc prevents the aggregation and ubiquitin-mediated degradation of the T-synthase. These results demonstrate that Cosmc is a molecular chaperone in the ER required for this branchpoint glycosyltransferase function and show that expression of the disease-related Tn antigen can result from deregulation or loss of Cosmc function